Antibiotic Resistance: A silent killer behind the curtains

The original article was published by Centre For Disease Control and Prevention. The Kashmir Radar published it with a little modification. ( Antibiotic Resistance)

Antibiotic resistance shows up when germs like bacteria and fungi develop the ability to resist the efficacy of drugs designed to kill them. That means the bacteria or fungi are not killed and they continue to grow.

Infections caused by antibiotic-resistant germs are not treated with ease, and sometimes it becomes impossible for the medical professionals to treat them. In most cases, antibiotic-resistant infections require prolonged hospital stays, more follow-up doctor visits, and expensive and toxic alternatives.

In technical terms, it is not the body that becomes resistant to antibiotics; it is that bacteria have developed resistantance to the antibiotics designed to kill them.

Antibiotic Resistance: A silent killer of modern times
Antibiotic Resistance: A leap from 1991 to 20221

Antibiotic Resistance Is A Threat To Everyone

Antibiotic resistance has the capability to affect people at any stage of life, as well as the healthcare, veterinary, and agriculture industries, making it one of the world’s most urgent public health problems.

Going by the statistics, each year in the U.S., at least 2.8 million people are infected with antibiotic-resistant bacteria or fungi, and more than 35,000 people die as a result.

No one can completely avoid the risk of resistant infections, but some people are found to be at a greater risk than others (for example, people with chronic illnesses). If antibiotics lose their effectiveness, then we lose the ability to treat infections.

Many medical advances are dependent on the ability to fight infections using antibiotics, including joint replacements, organ transplants, cancer therapy, and treatment of chronic diseases like diabetes, asthma, and rheumatoid arthritis.

Brief History of Resistance and Antibiotics

Penicillin, the first commercialized antibiotic, was discovered in 1928 by Alexander Fleming. Ever since, there has been discovery and acknowledgement of resistance alongside the discovery of new antibiotics. In fact, germs will always look for ways to survive and resist new drugs. More and more, germs are sharing their resistance with one another, making it harder for us to keep up.

Select Germs Showing Resistance Over Time
Antibiotic Approved or Released Year Released Resistant Germ Identified Year Identified
Penicillin 1941

Penicillin-resistant Staphylococcus aureus

Penicillin-resistant Streptococcus pneumoniae

Penicillinase-producing Neisseria gonorrhoeae





Vancomycin 1958
Plasmid-mediated vancomycin-resistant Enterococcus faecium

Vancomycin-resistant Staphylococcus aureus



Amphotericin B 1959 Amphotericin B-resistant Candida auris 2016
Methicillin 1960 Methicillin-resistant Staphylococcus aureus 1960
Extended-spectrum cephalosporins 1980 (Cefotaxime) Extended-spectrum beta-lactamase- producing Escherichia coli 1983
Azithromycin 1980 Azithromycin-resistant Neisseria gonorrhoeae 2011
Imipenem 1985 Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae 1996
Ciprofloxacin 1987 Ciprofloxacin-resistant Neisseria gonorrhoeae 2007
Fluconazole 1990 (FDA approved) Fluconazole-resistant Candida 1988
Caspofungin 2001 Caspofungin-resistant Candida 2004
Daptomycin 2003 Daptomycin-resistant methicillin-resistant Staphylococcus aureus 2004
Ceftazidime-avibactam 2015 Ceftazidime-avibactam-resistant KPC-producing Klebsiella pneumoniae 2015

News Desk

News Desk staff at The Kashmir Radar. Posting unbiased news as we believe in pure journalism!

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